New Drug Notices

This page illustrates Wolter Kluwer Clinical Drug Information's commitment to its publishing model. Our online and mobile app databases are updated daily, providing timely information on medications and vital healthcare topics.

Below is a list of new drug monographs that have been recently added to the Lexicomp core drug database.

View Complete Monographs

New drug monographs are available immediately to subscribers of Lexicomp Online and Mobile Apps.

New Drug Approvals

Generic Brand Pharmacologic Category
December 2017
Semaglutide Ozempic Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist
Letermovir Prevymis Antiviral Agent
November 2017
Anticoagulant Sodium Citrate TriCitraso Anticoagulant
Benralizumab Fasenra Interleukin-5 Receptor Antagonist; Monoclonal Antibody, Anti-Asthmatic
Emicizumab-kxwh Hemlibra Antihemophilic Agent; Monoclonal Antibody
Hepatitis B Vaccine Heplisav-B Vaccine; Vaccine, Inactivated (Viral); Vaccine, Recombinant
Letermovir Prevymis Antiviral Agent
Latanoprostene Bunod Vyzulta Ophthalmic Agent, Antiglaucoma; Prostaglandin, Ophthalmic
October 2017
Zoster Vaccine (Recombinant) Shingrix Vaccine; Vaccine, Recombinant
Axicabtagene Ciloleucel Yescarta Antineoplastic Agent, Anti-CD19; Antineoplastic Agent, CAR-T Immunotherapy; CAR-T Cell Immunotherapy; Cellular Immunotherapy, Autologous; Chimeric Antigen Receptor T-Cell Immunotherapy
September 2017
Abemaciclib Verzenio Antineoplastic Agent, Cyclin-Dependent Kinase Inhibitor
Copanlisib Aliqopa PI3 Kinase Inhibitor
August 2017
Benznidazole --- Antiprotozoal, Nitroimidazole; Antitrypanosomal
Tisagenlecleucel Kymriah Antineoplastic Agent, Anti-CD19; Antineoplastic Agent, CAR-T Immunotherapy; CAR-T Cell Immunotherapy; Cellular Immunotherapy, Autologous; Chimeric Antigen Receptor T-Cell Immunotherapy
Inotuzumab Ozogamicin Besponsa Antineoplastic Agent, Anti-CD22; Antineoplastic Agent, Antibody Drug Conjugate; Antineoplastic Agent, Monoclonal Antibody
Daunorubicin and Cytarabine (Liposomal) Vyxeos Antineoplastic Agent, Anthracycline; Antineoplastic Agent, Antimetabolite; Antineoplastic Agent, Antimetabolite (Pyrimidine Analog); Antineoplastic Agent, Topoisomerase II Inhibitor
Enasidenib Idhifa Antineoplastic Agent, IDH2 Inhibitor
July 2017
Neratinib Nerlynx Antineoplastic Agent, Anti-HER2; Antineoplastic Agent, Epidermal Growth Factor Receptor (EGFR) Inhibitor; Antineoplastic Agent, Tyrosine Kinase Inhibitor
Guselkumab Tremfya Antipsoriatic Agent; Interleukin-23 Inhibitor; Monoclonal Antibody
June 2017
Betrixaban Bevyxxa Anticoagulant; Anticoagulant, Factor Xa Inhibitor; Direct Oral Anticoagulant (DOAC)
Delafloxacin Baxdela Antibiotic, Fluoroquinolone
Factor IX (Recombinant [Glycopegylated]) Rebinyn Antihemophilic Agent
May 2017
Sarilumab Kevzara Antirheumatic, Disease Modifying; Interleukin-6 Receptor Antagonist; Monoclonal Antibody
Edaravone Radicava Free Radical Scavenger
Brigatinib Alunbrig Antineoplastic Agent, Anaplastic Lymphoma Kinase Inhibitor; Antineoplastic Agent, Tyrosine Kinase Inhibitor
April 2017
Midostaurin Rydap Multikinase Inhibitor
Abaloparatide Tymlos Parathyroid Hormone Analog
Cerliponase Alfa Brineura Hydrolytic Lysosomal N-terminal Tripeptidyl Peptidase
Valbenazine Ingrezza Central Monoamine-Depleting Agent; Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
Deutetrabenazine Austedo Central Monoamine-Depleting Agent; Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
March 2017
House Dust Mite Allergen Extract Odactra Allergen-Specific Immunotherapy
Ocrelizumab Ocrevus Anti-CD20 Monoclonal Antibody; Monoclonal Antibody
Dupilumab Dupixent Interleukin-4 Receptor Antagonist; Monoclonal Antibody
Niraparib Zejula Antineoplastic Agent, PARP Inhibitor
Naldemedine Symproic Gastrointestinal Agent, Miscellaneous; Opioid Antagonist, Peripherally-Acting
Avelumab Bavencio Antineoplastic Agent, Anti-PD-L1 Monoclonal Antibody; Antineoplastic Agent, Monoclonal Antibody
Safinamide Xadago Anti-Parkinson Agent, MAO Type B Inhibitor
Ribociclib Kisqali Antineoplastic Agent, Cyclin-Dependent Kinase Inhibitor
Telotristat Ethyl Xermelo Tryptophan Hydroxylase Inhibitor
February 2017
Deflazacort Emflaza Corticosteroid, Systemic
Brodalumab Siliq Antipsoriatic Agent; Interleukin-17A Receptor Antagonist; Monoclonal Antibody
Etelcalcetide Parsabiv Calcimimetic
January 2017
Plecanatide Trulance Gastrointestinal Agent, Miscellaneous; Guanylate Cyclase-C (GC-C) Agonist
Oxymetazoline (Topical) Rhofade Adrenergic Agonist Agent; Imidazoline Derivative
Prasterone Intrarosa Steroid, Synthetic
December 2016
Rucaparib Rubraca Antineoplastic Agent, PARP Inhibitor
Nusinersen Spinraza Antisense Oligonucleotide
Crisaborole Eucrisa Phosphodiesterase-4 Enzyme Inhibitor, Topical; Topical Skin Product
October 2016
Bezlotoxumab Zinplava Monoclonal Antibody
Olaratumab Lartruvo Antineoplastic Agent, Monoclonal Antibody; Antineoplastic Agent, PDGFR-alpha Blocker
September 2016
Eteplirsen Exondys 51 Antisense Oligonucleotide
July 2016
Lixisenatide Adlyxin Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist
Antihemophilic Factor (Recombinant [Fc Fusion Protein]) Eloctate Antihemophilic Agent
Lifitegrast Xiidra Lymphocyte Function-Associated Antigen 1 (LFA-1) Antagonist
June 2016
Levofloxacin (Oral Inhalation) Quinsair Antibiotic, Fluoroquinolone
Obeticholic Acid Ocaliva Farnesoid X Receptor Agonist
Gallium Ga 68 Dotatate Netspot Radiopharmaceutical
Calcifediol Rayaldee Vitamin D Analog
May 2016
Fluciclovine F 18 Axumin Radiopharmaceutical
Atezolizumab Tecentriq Antineoplastic Agent, Anti-PD-L1 Monoclonal Antibody; Antineoplastic Agent, Monoclonal Antibody
Pimavanserin Nuplazid Second Generation (Atypical) Antipsychotic
April 2016
Riboflavin 5'-Phosphate Photrexa Corneal Collagen Cross-Linking Agent, Ophthalmic; Ophthalmic Agent
Venetoclax Venclexta Antineoplastic Agent; Antineoplastic Agent, BCL-2 Inhibitor
March 2016
Ixekizumab Taltz Antipsoriatic Agent; Interleukin-17A Receptor Antagonist; Monoclonal Antibody
Reslizumab Cinqair Interleukin-5 Receptor Antagonist; Monoclonal Antibody, Anti-Asthmatic
Obiltoxaximab Anthim Antidote; Monoclonal Antibody
Factor IX (Recombinant [Albumin Fusion Protein]) Idelvion Antihemophilic Agent
Feburary 2016
Brivaracetam Briviact Anticonvulsant, Miscellaneous
January 2016
Lesinurad Zurampic Antigout Agent; URAT1 Inhibitor

New Drug Combinations

Generic Brand Pharmacologic Category
November 2017
Dolutegravir and Rilpivirine Juluca Antiretroviral, Integrase Inhibitor (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Non-nucleoside (Anti-HIV)
September 2017
Fluticasone, Umeclidinium, and Vilanterol Trelegy Ellipta Anticholinergic Agent; Anticholinergic Agent, Long-Acting; Beta2 Agonist; Beta2-Adrenergic Agonist, Long-Acting; Corticosteroid, Inhalant (Oral)
August 2017
Meropenem and Vaborbactam Vabomere Antibiotic, Carbapenem; Beta-Lactamase Inhibitor
Lesinurad and Allopurinol Duzallo Antigout Agent; Uric Acid Transporter 1 (URAT1) Inhibitor; Xanthine Oxidase Inhibitor
July 2017
Dexbrompheniramine and Phenylephrine Dallergy Alkylamine Derivative; Alpha-Adrenergic Agonist; Histamine H1 Antagonist; Histamine H1 Antagonist, First Generation
Sofosbuvir, Velpatasvir, and Voxilaprevir Vosevi Antihepaciviral, NS5A Inhibitor; Antihepaciviral, Polymerase Inhibitor (Anti-HCV); NS3/4A Inhibitor; NS5A Inhibitor; NS5B RNA Polymerase Inhibitor
June 2017
Rituximab and Hyaluronidase Rituxan Hycela Antineoplastic Agent, Anti-CD20; Antineoplastic Agent, Monoclonal Antibody
April 2017
Phenylephrine and Pramoxine Preparatation H Maximum Strength Alpha-Adrenergic Agonist; Antihemorrhoidal Agent; Local Anesthetic
February 2017
Dapagliflozin and Saxagliptin Qtern Antidiabetic Agent, Dipeptidyl Peptidase 4 (DPP-4) Inhibitor; Antidiabetic Agent, Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor; Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor
November 2016
Insulin Degludec and Liraglutide Xultophy Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist; Insulin, Long-Acting
Insulin Glargine and Lixisenatide Soliqua Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist; Insulin, Long-Acting
September 2016
Aspirin and Omeprazole Yosprala Analgesic, Nonopioid; Antiplatelet Agent; Nonsteroidal Anti-inflammatory Drug (NSAID), Oral; Proton Pump Inhibitor; Salicylate; Substituted Benzimidazole
August 2016
Oxycodone and Naltrexone Troxyca ER Analgesic, Opioid; Opioid Antagonist
July 2016
Tetracaine and Oxymetazoline Kovanaze Local Anesthetic
June 2016
Sofosbuvir and Velpatasvir Epclusa Antihepaciviral, NS5A Inhibitor; Antihepaciviral, Polymerase Inhibitor (Anti-HCV); NS5A Inhibitor; NS5B RNA Polymerase Inhibitor
Nebivolol and Valsartan Byvalson Angiotensin II Receptor Blocker; Antihypertensive; Antihypertensive, Combination; Beta-Blocker, Beta-1 Selective
April 2016
Glycopyrrolate and Formoterol Bevespi Aerosphere Anticholinergic Agent; Anticholinergic Agent, Long-Acting; Beta2 Agonist; Beta2-Adrenergic Agonist, Long-Acting
Emtricitabine and Tenofovir Alafenamide Descovy Antiretroviral, Reverse Transcriptase Inhibitor, Nucleoside (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleotide (Anti-HIV)
March 2016
Emtricitabine, Rilpivirine, and Tenofovir Alafenamide Odefsey Antiretroviral, Reverse Transcriptase Inhibitor, Non-nucleoside (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleoside (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleotide (Anti-HIV)
January 2016
Elbasvir and Grazoprevir Zepatier Antihepaciviral, NS5A Inhibitor; Antihepaciviral, Protease Inhibitor (Anti-HCV)