New Drug Notices

This page illustrates Wolter Kluwer Clinical Drug Information's commitment to its publishing model. Our online and mobile app databases are updated daily, providing timely information on medications and vital healthcare topics.

Below is a list of new drug monographs that have been recently added to the Lexicomp core drug database.

View Complete Monographs

New drug monographs are available immediately to subscribers of Lexicomp Online and Mobile Apps.

New Drug Approvals

Generic Brand Pharmacologic Category
March 2017
Niraparib Zejula Antineoplastic Agent, PARP Inhibitor
Naldemedine Symproic Gastrointestinal Agent, Miscellaneous; Opioid Antagonist, Peripherally-Acting
Avelumab Bavencio Antineoplastic Agent, Anti-PD-L1 Monoclonal Antibody; Antineoplastic Agent, Monoclonal Antibody
Safinamide Xadago Anti-Parkinson Agent, MAO Type B Inhibitor
Ribociclib Kisqali Antineoplastic Agent, Cyclin-Dependent Kinase Inhibitor
Telotristat Ethyl Xermelo Tryptophan Hydroxylase Inhibitor
February 2017
Deflazacort Emflaza Corticosteroid, Systemic
Brodalumab Siliq Antipsoriatic Agent; Interleukin-17A Receptor Antagonist; Monoclonal Antibody
Etelcalcetide Parsabiv Calcimimetic
December 2016
Rucaparib Rubraca Antineoplastic Agent, PARP Inhibitor
Nusinersen Spinraza Antisense Oligonucleotide
Crisaborole Eucrisa Phosphodiesterase-4 Enzyme Inhibitor, Topical; Topical Skin Product
October 2016
Bezlotoxumab Zinplava Monoclonal Antibody
Olaratumab Lartruvo Antineoplastic Agent, Monoclonal Antibody; Antineoplastic Agent, PDGFR-alpha Blocker
September 2016
Eteplirsen Exondys 51 Antisense Oligonucleotide
July 2016
Lixisenatide Adlyxin Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist
Antihemophilic Factor (Recombinant [Fc Fusion Protein]) Eloctate Antihemophilic Agent
Lifitegrast Xiidra Lymphocyte Function-Associated Antigen 1 (LFA-1) Antagonist
June 2016
Levofloxacin (Oral Inhalation) Quinsair Antibiotic, Fluoroquinolone
Obeticholic Acid Ocaliva Farnesoid X Receptor Agonist
Gallium Ga 68 Dotatate Netspot Radiopharmaceutical
Calcifediol Rayaldee Vitamin D Analog
May 2016
Fluciclovine F 18 Axumin Radiopharmaceutical
Atezolizumab Tecentriq Antineoplastic Agent, Anti-PD-L1 Monoclonal Antibody; Antineoplastic Agent, Monoclonal Antibody
Pimavanserin Nuplazid Second Generation (Atypical) Antipsychotic
April 2016
Riboflavin 5'-Phosphate Photrexa Corneal Collagen Cross-Linking Agent, Ophthalmic; Ophthalmic Agent
Venetoclax Venclexta Antineoplastic Agent; Antineoplastic Agent, BCL-2 Inhibitor
March 2016
Ixekizumab Taltz Antipsoriatic Agent; Interleukin-17A Receptor Antagonist; Monoclonal Antibody
Reslizumab Cinqair Interleukin-5 Receptor Antagonist; Monoclonal Antibody, Anti-Asthmatic
Obiltoxaximab Anthim Antidote; Monoclonal Antibody
Factor IX (Recombinant [Albumin Fusion Protein]) Idelvion Antihemophilic Agent
Feburary 2016
Brivaracetam Briviact Anticonvulsant, Miscellaneous
January 2016
Lesinurad Zurampic Antigout Agent; URAT1 Inhibitor
December 2015
Selexipag Uptravi Prostacyclin; Prostacyclin IP Receptor Agonist; Vasodilator
von Willebrand Factor (Recombinant) Vonvendi Antihemophilic Agent
Sugammadex Bridion Antidote; Selective Relaxant Binding Agent
Alectinib Alecensa Antineoplastic Agent, Anaplastic Lymphoma Kinase Inhibitor; Antineoplastic Agent, Tyrosine Kinase Inhibitor
Sebelipase Alfa Kanuma Enzyme, Replacement Therapy
Elotuzumab Empliciti Antineoplastic Agent, Monoclonal Antibody; Antineoplastic Agent, SLAMF7 Monoclonal Antibody
November 2015
Ixazomib Ninlaro Proteasome Inhibitor
Osimertinib TAGRISSO Antineoplastic Agent, Epidermal Growth Factor Receptor (EGFR) Inhibitor; Antineoplastic Agent, Tyrosine Kinase Inhibitor
Daratumumab Darzalex Antineoplastic Agent, Anti-CD38; Antineoplastic Agent, Monoclonal Antibody; Monoclonal Antibody
Antihemophilic Factor (Recombinant [Pegylated]) Adynovate Antihemophilic Agent
Mepolizumab Nucala Interleukin-5 Receptor Antagonist; Monoclonal Antibody, Anti-Asthmatic
October 2015
Talimogene Laherparepvec Imlygic Antineoplastic Agent, Oncolytic Virus
Asfotase Alfa Strensiq Enzyme
Rolapitant Varubi Antiemetic; Substance P/Neurokinin 1 Receptor Antagonist
Cariprazine Vraylar Second Generation (Atypical) Antipsychotic
Irinotecan (Liposomal) Onivyde Antineoplastic Agent, Camptothecin; Antineoplastic Agent, Topoisomerase I Inhibitor
Patiromer Veltassa Antidote
Factor X (Human) Coagadex Antihemophilic Agent; Blood Product Derivative
Idarucizumab Praxbind Antidote; Monoclonal Antibody
September 2015
Flibanserin Addyi Mixed 5-HT1A Agonist/5-HT2A Antagonist
Evolocumab Repatha; Repatha SureClick Antilipemic Agent, PCSK9 Inhibitor; Monoclonal Antibody
August 2015
Alirocumab Praluent Antilipemic Agent, PCSK9 Inhibitor; Monoclonal Antibody
Daclatasvir Daklinza Antihepaciviral, NS5A Inhibitor
Sonidegib Odomzo Antineoplastic Agent, Hedgehog Pathway Inhibitor
Brexpiprazole Rexulti Second Generation (Atypical) Antipsychotic

New Drug Combinations

Generic Brand Pharmacologic Category
February 2017
Dapagliflozin and Saxagliptin Qtern Antidiabetic Agent, Dipeptidyl Peptidase 4 (DPP-4) Inhibitor; Antidiabetic Agent, Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor; Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor
November 2016
Insulin Degludec and Liraglutide Xultophy Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist; Insulin, Long-Acting
Insulin Glargine and Lixisenatide Soliqua Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist; Insulin, Long-Acting
September 2016
Aspirin and Omeprazole Yosprala Analgesic, Nonopioid; Antiplatelet Agent; Nonsteroidal Anti-inflammatory Drug (NSAID), Oral; Proton Pump Inhibitor; Salicylate; Substituted Benzimidazole
August 2016
Oxycodone and Naltrexone Troxyca ER Analgesic, Opioid; Opioid Antagonist
July 2016
Tetracaine and Oxymetazoline Kovanaze Local Anesthetic
June 2016
Sofosbuvir and Velpatasvir Epclusa Antihepaciviral, NS5A Inhibitor; Antihepaciviral, Polymerase Inhibitor (Anti-HCV); NS5A Inhibitor; NS5B RNA Polymerase Inhibitor
Nebivolol and Valsartan Byvalson Angiotensin II Receptor Blocker; Antihypertensive; Antihypertensive, Combination; Beta-Blocker, Beta-1 Selective
April 2016
Glycopyrrolate and Formoterol Bevespi Aerosphere Anticholinergic Agent; Anticholinergic Agent, Long-Acting; Beta2 Agonist; Beta2-Adrenergic Agonist, Long-Acting
Emtricitabine and Tenofovir Alafenamide Descovy Antiretroviral, Reverse Transcriptase Inhibitor, Nucleoside (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleotide (Anti-HIV)
March 2016
Emtricitabine, Rilpivirine, and Tenofovir Alafenamide Odefsey Antiretroviral, Reverse Transcriptase Inhibitor, Non-nucleoside (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleoside (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleotide (Anti-HIV)
January 2016
Elbasvir and Grazoprevir Zepatier Antihepaciviral, NS5A Inhibitor; Antihepaciviral, Protease Inhibitor (Anti-HCV)