Trissel's™2 Clinical Pharmaceutics Database:
Click on "Trissel's IV Compatibility" to open the module.
To search on compatibility information, begin by typing the desired drug or solution name into the appropriate search box. Possible drug/solution selections will be displayed as you continue to type. Select a drug or solution by clicking the enter key on your keyboard or by using the Add button. You will need to enter at least 2 drugs or at least one drug and solution into the respective search boxes to create the compatibility table.. The selected drug(s) and solution(s) will populate the Selected Items in the left pane. Once the desired items have been entered, click the blue Analyze button to perform the compatibility check.
The results will be presented in a table with the drugs in both horizontal and vertical axis. Solutions, if selected, will be listed underneath the drugs on the vertical axis. To locate the results of a desired drug-drug or drug-solution pair, follow the horizontal and vertical axis to find where they intersect. The field will contain the different compatibility tests available for the desired pair. To filter the compatibility types to only view Y-site compatibilities, change the filter in the upper right pane from “All methods” to “Y-Site only”.
Definitions for the following types of compatibility testing are as follows:
|Y-site Compatibility||A single drug that is administered simultaneously at a Y-site connection with another drug in a solution|
|Solution Compatibility||A single drug in a solution|
|Admixture Compatibility||Two drugs in a solution|
|Syringe Compatibility||Two drugs in a syringe|
The compatibility information presented is based on one of four (4) ratings:
|Uncertain or Variable||
For research results that do not fit these conventional guidelines, the research results are designated as Uncertain or Variable. Apply judgment in using these results. Examples include:
|No data||No data for administration methods chosen.|
Click on the rating link in the table to obtain additional details on the compatibility study(s), including a summary of the study methods and references for the compatibility information as appropriate. If multiple studies are available, click on the desired link within either the Study or Finding columns. The tabs at the top of the page will return you to the Compatibility Chart or the Search page.
To find all drugs and solutions that are compatible for a single drug, click on the drug name in the “Selected Items” List. This will create a list of drugs and solutions that have compatibility information available for that drug.
You can use the filter menu on the right to narrow the results to a specific type of compatibility.
In addition, when the drug name is clicked, a second tab opens to display the specific pharmaceutical properties for a particular drug. (Items listed in the Solutions section will have only the tab for the pharmaceutical properties information available). These monographs may include: formulation or reconstitution information, stability and storage information, light effects, pH, and various other information.
You can click on the Search tab at any time to enter new drugs to be screened. New items will appear in the Selected Items field. To remove an individual drug or solution, click on the X next to the name. To clear the items from the tool, click the Clear button.
- The Lexicomp Online Home Page
- Browse by Category
- Reviewing Search Results
- Accessing Information Within a Drug Monograph
- Accessing Clinical Tools
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