Drug Indications

Help Prevent Inappropriate Prescribing with Advanced Clinical Information Systems

What It Does for Your Business

  • Assists in identifying the drugs available to treat a specific medical condition in order to:
    • Facilitate adherence to federal drug use standards
    • Identify potential off-label drug uses and drug contraindications associated with inappropriately prescribed medications
  • Allows differentiation between labeled and common off-label drug uses
  • Helps professionals assess appropriate drug selection, including during e-prescribing
  • Helps avoid hospitalizations, physician office visits, drug therapy, lab tests and other costs associated with inappropriate drug selection
  • Optimizes therapeutic outcomes by identifying drugs that are typically used in combination with other drugs to manage a condition
  • Supports “proxy” medical condition identification, enabling users to infer medical conditions based on drug therapy when other information is unavailable
  • Assists in identifying chronic conditions defined by CMS as eligible for MTM services, thus helping to identify eligible patients - Learn more about the MTM Toolkit

What It Provides

  • The ability to search and retrieve drugs available to treat a specific medical condition
  • Qualifying conditions – defines any additional condition, disease, population, etc., that must be present for a condition to apply
  • Identifies if the drug has been approved by the U.S. Food and Drug Administration (FDA) for the indication
  • Documentation source – defines the source of the indication
  • Documentation level – includes the quality and quantity of supporting information
  • Drug acceptance level - helps differentiate between FDA-approved indications, medically recognized unlabeled uses and other known unlabeled uses
  • Therapy duration - distinguishes between short-term use and maintenance drugs
  • Outcome - specifies the “expected” clinical result subsequent to drug use
  • Additional text provided to further describe the drug-to-indication that is not adequately described by one of the defined attributes

Delivery and Required Solutions

Delivery Options


  • API: Medi-Span Clinical Drug Indications API (Also available via Web Services)
  • Flat File: Drug Indications Database


  • Weekly
  • Monthly


Why Medi-Span?

Overall Satisfaction


of customers are satisfied with the quality of Medi-Span data

Renewal Rate


of customers are likely to renew their Medi-Span data license



Hundreds of customers see 50% or greater increase in productivity with Medi-Span

See why more healthcare businesses are choosing Medi-Span for their drug data:

Reasons Customers Chose and Stay


  • Speed to Market

    Medi-Span implementation support helped save me one month in speed to market and about $10,000 in development costs.

    Keith Streckenbach, CEO
    HighFive Health

  • Fast Results

    Medi-Span, in my view, beats everyone else. It helps you find twice as many drug errors – errors that would lead to readmission - in half the amount of time.

    Keith Streckenbach, CEO
    HighFive Health

  • Competitive Advantage

    (Medi-Span) allows us to provide features that our competitors do not have.

    Senior developer from a healthcare software vendor

  • Valuable Resource

    As a claims processor, we rely on Medi-Span and its wealth of drug information to forecast and price claims for our clients. Medi-Span is the go-to (application) that is recognized across the industry for (manufacturer-provided) drug information. They have innovative tools and excellent customer service that will go above and beyond to provide the best available solution.

    Healthcare vendor systems analyst

  • Valuable Support

    Medi-Span implementation support helped save me one month in speed to market and about $10,000 in development costs.”

    Keith Streckenbach, CEO HighFive Health

  • Consistent Pricing Data

    It is the source for the benchmark prices consistently used in the PBM industry and the tool we use to hold PBMs accountable to their pricing promises to our employers.

    Insurance company senior actuarial consultant

  • Business Essential

    Business cannot survive without Medi-Span data.

    Fortune 500 PBM clinical pharmacist

  • Key Content

    Only reliable published resource for (manufacturer-provided) AWP. (Medi-Span proprietary) GPI is therapeutic classification system of choice. It is very enabling, as clinical management rules are easily articulated.

    Chief Pharmacy Officer from a PBM

  • Provides Confidence

    Even in an era where data abounds, there is a terrific amount of uncertainty. People want confidence that what they are seeing is (based on) real (manufacturer-provided information) – Medi-Span provides that confidence.

    Health plan executive

  • Unifying Data

    (Medi-Span) allows for consistency across the company, industry and clients.

    Manager from an insurance company

  • Timely and Relevant

    The Medi-Span database allows our system to have the latest and most current information available. It is especially needed for package information, interaction checking, and clinical printing.

    Executive from a healthcare software vendor

  • Strong Foundation

    This is a foundational piece that is used throughout the organization in many systems and is often used to connect data from multiple systems.

    Systems analyst from a top-grossing PBM


Who is Clinical Drug Information?

With the move to team-based care, conflicting data can lead to actual conflicts – from disparity in business decisions to confusion in communication. We research, validate, and synthesize content to show the right data to right people at the right time. With content developed in a consistent manner across all platforms and resources, your team receives aligned drug information no matter when or how they access it. This helps:

  • Improve communication
  • Reduce confusion
  • Enhance patient care

Learn more

Impacting thousands of healthcare organizations - see our story

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How can our award-winning drug data help you?

Learn more about Medi-Span